CyBio FeliX Liquid Handling Platform from Analytik Jena

Product Specs
ItemCyBio FeliX Liquid Handling Platform
CompanyAnalytik Jena
Price Get Pricing Get Quote for this Product
Catalog NumberCyBio FeliX
Dimensions(WxDxH) 650 x 450 x 700 mm
Capacity12 positions for microplates, tube racks, reservoirs and tips
ApplicationsPlate replication and reformatting / Serial dilution in rows and columns / Cherry picking / Tube or plate filling / Tube to plate transfer / Sample / reparation for PCR clean-up / DNA extraction and purification / Next Generation Sequencing (NGS) / HTRF assay / ADME and cytotoxicity assays
QuantityEA
Electrical Requirements115V and 230V models available

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Local Office

Analytik Jena

3 Highwood Drive

Suite 103E

Tewksbury, MA 01876

United States

Phone: 1.800.452.6788

Email: info@us.analytik-jena.com

Company Profile

Website: https://www.analytik-jena.us/

International Office

Analytik Jena

Konrad-Zuse-Strasse 1

07745 Jena

Germany

Phone: +49 3641 77 7444

Company Profile

Website: https://www.analytik-jena.com/

(1) Pervasive RNA folding is crucial for narnavirus genome maintenanceProceedings of the National Academy of SciencesJune 27, 2023Makiha Fukuda, Jitong Cai, Joel S. Bader, Jef D. Boekeextraction with the combined use of Quick- ‐DNA/RNA Viral MagBead Automated Kit (Zymo Research, R2141) and CyBio Felix automated liquid handler (Analytik Jena). Two microliters of total nucleic samples was subjected to

(2) Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?Fluids and Barriers of the CNSDecember 3, 2022Hans-Wolfgang Klafki, Barbara Morgado, Oliver Wirths, Olaf Jahn, Chris Bauer, Hermann Esselmann, Johannes Schuchhardt, Jens WiltfangAβ-immunoprecipitation Aβ-peptides were immunoprecipitated from EDTA-blood plasma samples in a semi-automated fashion using the CyBio FeliX liquid handling instrument (Analytik Jena, Jena, Germany) following a modified version of our previously

(3) LPS-induced lipid alterations in microglia revealed by MALDI mass spectrometry-based cell fingerprinting in neuroinflammation studiesScientific ReportsDecember 1, 2022Martina Blank, Thomas Enzlein, Carsten HopfMALDI-TOF mass spectrometry Automated preparation of cells on MALDI MS target plates (MTP) was done with a CyBio® FeliX pipetting platform (Analytik Jena AG, Germany). 96-well plates with frozen cells were taken out of the

(4) Extended longevity geometrically-inverted proximal tubule organoidsBiomaterialsNovember 1, 2022Eric Parigoris, Ji-Hoon Lee, Amy Yunfan Liu, Xueying Zhao, Shuichi Takayamaincubated at 37°C and 5% CO2. After 72 hours, 3 consecutive media changes were performed using the Cybio FeliX liquid handler (Analytik Jena), each removing 9 μL and adding 10 μL. Media changes were then performed

(5) Evaluation of the impact of pre-analytical conditions on sample stability for the detection of SARS-CoV-2 RNAJournal of Virological MethodsNovember 1, 2022Lucy Mosscrop, Patricia Watber, Paul Elliot, Graham Cooke, Wendy Barclay, Paul S. Freemont, Carolina Rosadas, Graham P. Taylor1B). 2.2 RNA extraction and RT-PCR For all samples, viral RNA was extracted using an automatic platform (CyBio FeliX liquid handler) with the innuPREP Virus DNA/RNA Kit (Analytik Jena) as previously described (Crone et

(6) High—throughput and automated screening for COVID-19Frontiers in Medical TechnologySeptember 15, 2022Nestor Jonguitud-Borrego, Koray Malcı, Mihir Anand, Erikan Baluku, Calum Webb, Lungang Liang, Carlos Barba-Ostria, Linda P. Guaman, Liu Hui, Leonardo Rios-SolisBiofoundry, where three different automated workflows were developed. By using Analytik Jena's (Germany) CyBio FeliX and Labcyte's (USA) Echo 525 liquid handling platforms, workflows involving RT-qPCR, CRISPR-Cas13a,

(7) Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitationAlzheimer's Research & TherapySeptember 7, 2022Hans-W. Klafki, Jonathan Vogelgsang, Ekaterina Manuilova, Chris Bauer, Alexander Jethwa, Hermann Esselmann, Anke Jahn-Brodmann, Dirk Osterloh, Ingolf Lachmann, Benedict Breitling, et al.described in detail previously [21]. The semi-automated pre-analytical magnetic bead IP was performed on a CyBio FeliX liquid handling Instrument (Analytik Jena) equipped with BioShake 3000-Telm (Q Instruments, Germany)

(8) The DevTox Germ Layer Reporter Platform: An Assay Adaptation of the Human Pluripotent Stem Cell TestToxicsJuly 13, 2022John T. Gamble, Kristen Hopperstad, Chad Deisenrothaspirated from the assay plate at a rate of 1 µL/s and 40 µL of Medium A ± test chemical applied using a CyBio FeliX automated liquid handler (Analytik Jena, Jena, Germany). At 24 h, conditioned cell culture medium was

(9) Mass spectrometry-based draft of the mouse proteomeNature MethodsJuly 1, 2022Piero Giansanti, Patroklos Samaras, Yangyang Bian, Chen Meng, Andrea Coluccio, Martin Frejno, Hannah Jakubowsky, Sophie Dobiasch, Rashmi R. Hazarika, Julia Rechenberger, et al.automated incubator (Thermo Fisher Scientific), cells were treated with the compound library using a CyBio® FeliX pipetting platform (Analytik Jena). All compounds were obtained from SelleckChem dissolved either in

(10) Identification of treatment‐induced vulnerabilities in pancreatic cancer patients using functional model systemsEMBO Molecular MedicineApril 7, 2022Katja Peschke et al.automated incubator (Thermo Fisher Scientific), the cells were treated with a compound library using a CyBio® FeliX pipetting platform (Analytik Jena, Jena, Germany). All compounds were obtained from SelleckChem. Each

(11) Optimization of Human Neural Progenitor Cells for an Imaging-Based High-Throughput Phenotypic Profiling Assay for Developmental Neurotoxicity ScreeningFrontiers in ToxicologyFebruary 16, 2022Megan Culbreth, Johanna Nyffeler, Clinton Willis, Joshua A. Harrillexamined. Prior to cell plating, PLO was removed, and the plates were washed one time with ddH2O using a CyBio FeliX (Felix; Analytik Jena) automated pipette robot. Finally, laminin (final concentration 20 µg/ml unless

(12) High-throughput formation and image-based analysis of basal-in mammary organoids in 384-well platesScientific reportsJanuary 10, 2022Lee S, Chang J, Kang SM, Parigoris E, Lee JH, Huh YS, Takayama S.3 of organoid culture, the media was exchanged 3 times to wash out the seeding supplements using a CyBio FeliX liquid handling machine (Analytik Jena). This culture media was supplemented with 0–100 ng/mL growth

(13) Continous, non-invasive monitoring of oxygen consumption in a parallelized microfluidic in vitro system provides novel insight into the response to nutrients and drugs of primary human hepatocytesEXCLI JJanuary 7, 2022Marius Busche, Dominik Rabl, Jan Fischer, Christian Schmees, Torsten Mayr, Rolf Gebhardt, Martin Stelzleseeding of cells All steps, which are not stated as “manually” were performed with a pipetting robot (CyBio FeliX, Analytik Jena, Jena, Germany) modified by Ionovation (Bissendorf, Germany). The priming and handling

(14) Highly sensitive and specific detection of the SARS-CoV-2 Delta variant by double-mismatch allele-specific real time reverse transcription PCRJournal of Clinical VirologyJanuary 1, 2022Jeremy A. Garson, Samuel Badru, Eleanor Parker, Richard S. Tedder, Myra O. McClurefor successful sequencing. 2.4 RNA extraction Viral RNA was extracted from clinical samples with a CyBio Felix liquid handing robot (Analytik Jena) and InnuPREP Virus DNA/RNA Kit (Analytik Jena), used according

(15) Rapid design and implementation of an adaptive pooling workflow for SARS-CoV-2 testing in an NHS diagnostic laboratory: a proof-of-concept studyWellcome Open ResearchOctober 13, 2021Michael Crone, Paul Randell, Zoey Herm, Arthi Anand, Saghar Missaghian-Cully, Loren Perelman, Panagiotis Pantelidis, Paul FreemontA sample of 200 μl was used for RNA extraction using the Maxwell HT Viral TNA kit (Promega) on the CyBio FeliX liquid handler (Analytik Jena) with an elution volume of 50 μl. Subsequent RT-qPCR was performed using

(16) Optimized protocol for a quantitative SARS-CoV-2 duplex RT-qPCR assay with internal human sample sufficiency controlJournal of Virological MethodsAugust 1, 2021Aileen G. Rowan et al.(Pastorino et al., 2020). 2.3 RNA extraction The RNA extraction of SARS-CoV-2 was performed on the CyBio FeliX liquid handling robot (Analytik Jena), as previously described (Crone et al., 2020), using the Maxwell

(17) High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblastsEMBO molecular medicineJune 7, 2021Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T.cholesterol ester), and TAG (D5 TAG mix I). Extraction was performed using automated liquid handling robot (CyBio FeliX, Analytik Jena) according to Bligh and Dyer with modifications. Briefly, 7.5 µg mitochondria or 1 ×

(18) Cancer Cell Invasion of Mammary Organoids with Basal-In PhenotypeAdvanced healthcare materialsFebruary 1, 2021Parigoris E, Lee S, Mertz D, Turner M, Liu AY, Sentosa J, Djomehri S, Chang HC, Luker K, Luker G, et al.3 of organoid culture, the media was exchanged 3 times to wash out the seeding supplements using a CyBio FeliX liquid handling machine (Analytik Jena). To exchange media, 9 μL was removed, and 10 μL was added to

(19) A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnosticsNature CommunicationsDecember 1, 2020Michael A. Crone, Miles Priestman, Marta Ciechonska, Kirsten Jensen, David J. Sharp, Arthi Anand, Paul Randell, Marko Storch, Paul S. Freemontplatform in combination with SAS JMP software. VLP RNA extraction was optimized for the Analytik Jena CyBio FeliX liquid-handling platform for the standard 96-well plate format using the innuPREP Virus DNA/RNA Kit-FX. We prepared two VLP dilutions

(20) BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancerEBioMedicineOctober 1, 2020Lui GYL, Shaw R, Schaub FX, Stork IN, Gurley KE, Bridgwater C, Diaz RL, Rosati R, Swan HA, Ince TA, et al.were seeded at ~30% confluence in 384-well microtiter plates. The next day, drugs were added using a CyBio FeliX liquid handler (Analytik Jena AG), and cells were further incubated for an additional 144 h. Cell viability

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